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Expert insights on gabapentin and pregnancy safety considerations. Learn about risks, benefits, and medical recommendations for managing this medication during pregnancy. It is not known if gabapentin can make it harder to get pregnant. Sexual dysfunction (including loss of desire to have sex and loss of ability to have an orgasm) has been reported among people who take gabapentin. Does taking gabapentin increase the chance of miscarriage? Gabapentin and Pregnancy - Gabapentin - GabapentinTo provide information regarding the effects of in utero exposure to gabapentin, physicians are advised to recommend that pregnant patients taking gabapentin enroll in the North American Antiepileptic Drug (NAAED) Pregnancy Registry. How Gabapentin Can Be Addictive Mechanism: Gabapentin affects the brain’s neurotransmitters, particularly by Learn about gabapentin use in pregnancy and breastfeeding, including potential risks, benefits, and alternatives. Find out how gabapentin can affect fertility, miscarriage, birth defects, and baby development. Gabapentin in pregnancy and the risk of adverse neonatal and maternal outcomes: A population-based cohort study nested in the US Medicaid Analytic eXtract dataset. Gabapentin is an antiepileptic drug used for various conditions, but its safety in pregnancy is unclear. A large study found no evidence of major malformations, but a slightly higher risk of preterm birth, small for gestational age, and NICU admissions. Gabapentin is a pregnancy category C drug that may increase the risk of embryo fetal toxicity, preterm births and low birth weight. Learn about the animal studies, human research and alternatives for gabapentin use during pregnancy. In this large population-based study, we did not find evidence for an association between gabapentin exposure during early pregnancy and major malformations overall, although there was some evidence of a higher risk of cardiac malformations. Maternal use of gabapentin, particularly late in pregnancy While gabapentin (Neurontin) is now used in a wide variety of clinical settings — for epilepsy, pain management, restless leg syndrome, anxiety, and sleep disturbance – there is relatively little information regarding its reproductive safety. Most recently, a prospective study from researchers at the Motherisk program reports on the outcomes of 223 pregnancies exposed to gabapentin Gabapentin is not generally recommended in pregnancy as there is not enough information about its safety. It may cause withdrawal symptoms in newborn babies and should only be taken if the benefits outweigh the risks. This sheet discusses gabapentin use during pregnancy and breastfeeding, offering guidance on potential risks and safety considerations. In a cohort study of pregnant women included in the US Medicaid Analytic eXtract (MAX) dataset, Elisabetta Patorno and colleagues investigate neonatal and maternal outcomes associated with gabapentin exposure during pregnancy. Gabapentin (Neurontin®) is mainly used to treat epilepsy and nerve pain, and to prevent migraine. What are the benefits of taking gabapentin in pregnancy? Gabapentin prevents epileptic seizures, which can be dangerous to the woman and also lead to pregnancy complications. Is gabapentin safe during pregnancy? Learn about the potential risks and benefits of taking gabapentin while pregnant, and what you should discuss with your doctor. Despite the widespread use, only sparse information is available on the safety of gabapentin during pregnancy. We sought to evaluate the association between gabapentin exposure during pregnancy and risk of adverse neonatal and maternal outcomes. This article summarizes the current literature regarding gabapentin use during pregnancy and related prenatal and neonatal exposure outcomes with special consideration for interactions between gabapentin and opioid use. Maternal use of gabapentin, particularly late in pregnancy, was associated with a higher risk of PTB, SGA, and NICUa. We have data on 223 pregnancy outcomes exposed to gabapentin and 223 unexposed pregnancies. The rates of major malformations were similar in both groups (p = 0.845). There was a higher rate of preterm births (p = 0.019) and low birth weight <2,500 g (p = 0.033) in the gabapentin group. Methods A systematic review was performed in PubMed and Reprotox using the search terms: “gabapentin”, “pregabalin”, “antiepileptic drugs” and terms associated with pregnancy. We included all studies in English that reported on the use and safety of gabapentin and pregabalin during pregnancy. Gabapentin is an antiepileptic drug that may cause birth defects and harm the fetus. Learn about the risks, benefits, and alternatives of using gabapentin during pregnancy and breastfeeding.
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