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To the Editor: The anticonvulsants valproate and carbamazepine have gained increasing popularity in the treatment of bipolar disorder and other conditions involving affect or impulse dysregulation. As with lithium, however, a major adverse effect of these drugs is weight gain. While the newer anticonvulsants lamotrigine and gabapentin have generated interest as possible mood stabilizers, their Topamax is more likely to be used for mood stabilization and weight loss, while Gabapentin is used commonly for anxiety.” – Talkspace psychiatrist Dr. Dion Metzger Topamax, originally approved for treating epilepsy and migraines, is also known to cause weight loss as a side effect, but is not FDA-approved for weight loss alone. The weight loss effect of Topamax is attributed to its ability to reduce appetite and possibly increase metabolism, with clinical trials showing a weight loss of 6%-17% in patients. Gabapentin and pregabalin are common chronic pain medications that are linked to weight gain. On the other hand, topiramate is associated with significant weight loss. Obesity, depression and chronic pain experts recommend avoiding medications that can increase body weight if another effective alternative is available. Topamax (topiramate) is a prescription tablet or capsule used to prevent migraine and treat epilepsy. Learn about its side effects, uses, dosage, and more. Topamax (topiramate) is used off-label for weight loss in obesity treatment. Learn more about why it’s used, whether it’s effective, and who should and shouldn’t take it. Topiramate mechanism of action. This figure was adapted with permission from [7]. 3.2. Mechanism of Action in Relation to Weight Loss Although the biological mechanism behind TPM-induced weight loss is not well-described, possible mechanisms include lowering calorie intake, decreased fat gain, and decreased triglycerides and cholesterol levels [8]. Studies show that TPM reduces energy The connection between gabapentin and weight loss (or more accurately, weight gain) is multifaceted and not fully understood․ While weight gain is a common side effect reported by many patients, the underlying mechanisms are still under investigation․ The variability in individual responses highlights the importance of a personalized Compare Gabapentin vs Topiramate head-to-head with other drugs for uses, ratings, cost, side effects and interactions. A Moderate Drug Interaction exists between gabapentin and Topamax. View detailed information regarding this drug interaction. Topiramate (Topamax) and gabapentin (Neurontin) are both antiepileptic medications, but they have different uses and dosing schedules. Topiramate is used to treat various types of seizures and to prevent migraines, while gabapentin is used for nerve pain from shingles and as an add-on treatment for partial seizures. Topiramate is available in both immediate-release and extended-release forms Topiramate has one huge advantage over many other psychotropics: it causes weight loss -not gain. While gabapentin caused an average gain of 2.2 kg during randomized trials (nearly as much as olanzapine’s 2.4 kg and worse than quetiapine’s 1.1 kg), topiramate caused an average loss of 3.8 kg. 3 Can I use Topamax for weight loss? Does Topamax cause weight loss? Learn all about using Topamax as a weight loss solution. We would like to show you a description here but the site won’t allow us. Compare Gabapentin vs Topamax head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Topamax‚ also known as topiramate‚ is a medication primarily prescribed for the treatment of epilepsy‚ migraines‚ and other neurological conditions. In recent years‚ it has gained attention for its potential weight loss benefits‚ leading many to explore its use as an off-label treatment for obesity. Gabapentin and Topamax, anyone have experience? So I started taking Topamax about a month ago for chronic migraines (25mg a day), I’m supposed to go up to 100mg over the next couple weeks. I’m currently taking 1300mg of gabapentin a day for nerve pain due to complications of my wisdom teeth long story. However, weight gain was a common side effect associated with gabapentin (7.5% of patients) while weight loss was linked to topiramate (22.5% of patients) [157]. Topamax (topiramate) is a seizure medication that’s also an off-label treatment for weight loss. Learn how Topamax for weight loss is used and tips before taking it. Gabapentin and Topamax for Weight Loss: What You Need to Know – NutriphyIntroduction The quest for effective and safe weight loss solutions is a constant pursuit, with various approaches, including medications, gaining attention․ Among these, gabapentin and topiramate, originally developed for different medical conditions, have emerged as potential weight loss aids․ While they may offer
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