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Oral gabapentin in cats – often without additional sedation/premedication – can be used by house-call and clinic-bound veterinarians to facilitate examination, blood draws, cystocentesis and additional injections. In cats, the gabapentin dose is 50-200 mg/cat (not per kg) depending on the size of the cat and the fear/fractiousness level. The dose for dogs is 10-20 (up to 40) mg/kg. Weight-Based Dosage: Gabapentin is dosed per kilogram of body weight, so the dose for kittens is significantly smaller than for adult cats. Developmental Stage: Young kittens may metabolize gabapentin differently, requiring adjustments to prevent sedation or other side effects. Give oral anxiolytic at home 2-3 hours prior to visit. Options: Gabapentin 20 mg/kg PO 2 - 3 hours prior to leaving home. Trazodone approx. 10 mg/kg PO 2 hours prior to leaving home. Liquid preparations can facilitate administration of the medication and accuracy of dosing. If your cat is experiencing anxiety or pain, find out how gabapentin can help, proper dosage, side effects, and more. Oral gabapentin in cats – often without additional sedation/premedication – can be used by house-call and clinic-bound veterinarians to facilitate examination, blood draws, cystocentesis and additional injections. For Sedation: A fixed range of 40-70 mg for smaller and older cats, or 75-90 mg for adult cats For example, a 10-pound cat being treated for seizures would have a recommended dosage range of about 20-50 mg of Gabapentin, administered orally twice a day. From a safety perspective, a gabapentin dosage for cats will typically not exceed 50-100mg per cat to address pain or when being used as a sedative. As a sedative, it is often given the night before and again 2-3 hours prior to an examination at the vet clinic or before getting in the car or on a plane. For sedation and calming, vets usually prescribe 40-70mg for smaller and old felines and 75-90mg for adult cats 2-3 hours before a vet visit or travel. Like other medicines, the safe dosage of gabapentin depends on the size of the cat, body weight and overall health condition. This study set out to investigate the effect of giving a single dose of gabapentin for fear-based aggressive behaviors in cats during veterinary visits. The researchers compared a dose of either 100 or 200 mg/cat to placebo capsules 2 hours prior to the vet visit. Correlations between favorable outcomes were measured based on compliance scores. Gabapentin is used to treat pain, anxiety, and seizures in cats. The standard dose of gabapentin for cats is 50 milligrams. Side effects like sedation, ataxia, hypersalivation, and vomiting may occur. For sedation and to manage anxiety, gabapentin doses in cats may be higher than when used for pain. The dose range for most cats is 50 mg to 200 mg and rarely exceeds 200 mg. RESULTS Owner-assessed cat stress scores during transportation and veterinary examination and veterinarian-assessed compliance scores were significantly lower when cats received gabapentin than when they received the placebo. Sedation was a common effect of gabapentin administration, and ataxia, hypersalivation, and vomiting were also reported. With use of a liquid gabapentin we can dose our cats really accurately with that optimal dose of 20 mg/kg. In a recent study (Gurney et al) we evaluated the efficacy of 20mg/kg gabapentin in hyperthyroid cats, given 1-2hrs before coming to the clinic. Key takeaways Gabapentin is used to treat nerve pain, chronic pain, and seizures. It’s also a mild sedative before veterinary visits or other stressful events. Veterinarians sometimes use it to treat feline hyperesthesia syndrome, depending on the suspected cause. The standard gabapentin dosage for cats is 3–20 mg/kg every six to 24 hours. The most common side effects of gabapentin in cats Anxiolytic, Sedation, and Premedication Drug Combinations Use this chart to determine which drug-class combinations may benefit your individual patients based on their health, demeanor, and the reason they require medication, including simply to calm their nerves. Clinical studies showed the Schedule V controlled substance to be efficacious for reducing acute feline fear during transportation and veterinary visits. Healthy cats exhibited minimal sedation and side effects. Compared with gabapentin, pregabalin is more potent, requires a smaller dose, and has a longer duration of action. Take-Home Points Dosage is an important consideration when using Gabapentin for sedation in cats. The dosage will vary depending on the cat 's weight, age, and overall health. It is important to follow your veterinarian's instructions carefully when administering Gabapentin to your cat to ensure that it is safe and effective. Gabapentin, an anticonvulsant used in the treatment of neuropathic pain, has been shown to reduce anxiety in rats and humans. 1,2 Although gabapentin’s anxiolytic properties have not been studied in cats, pharmacokinetics studies have reported excellent oral bioavailability and a wide margin of safety with single-dose administration. 3 Oral gabapentin in cats – often without additional sedation/premedication – can be used by house-call and clinic-bound veterinarians to facilitate examination, blood draws, cystocentesis, blood glucose curves, ultrasound exams and additional injections.
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