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No signi cant reduc-fi tion in lameness level was observed while receiving either gabapentin dose when compared with the placebo group. Further studies are necessary to determine effective plasma concentration and length of treatment period after PO administered gabapentin for analgesia in horses with chronic lameness. 2015 Elsevier Inc. To evaluate the analgesic effects of orally administered gabapentin on horses with chronic thoracic limb lameness. To evaluate the analgesic effects of orally administered gabapentin on horses with chronic thoracic limb lameness. Our results suggest that horses tolerate gabapentin up to 120 mg/kg PO q 12 h for 14 days. The analgesic effect of the dosage regimens evaluated in our study warrants further research. What condition was gabapentin prescribed for? What were your results? Were there side effects or complications? How long did you keep your horse on it? What dosage? And did you titrate up and taper down? Any other details you want to share I’m trying to collect as much info as possible about actual gabapentin usage. It came up in my recent NQR thread and I think it might be useful for my 1. INTRODUCTION Limited scientific information exists regarding the effective and safe dosing of gabapentin in horses. Based on clinical experience and anecdotal reporting, 1 the most commonly used dosage of gabapentin is either 10 or 20 mg/kg 2 , 3 which by itself is often ineffective at controlling pain from laminitis or osteoarthritis. View peer-reviewed research and journal articles on Gabapentin for horses. Explore its effects, therapeutic uses, and safety in equine medicine. The repeated administration of high doses of gabapentin may provide better analgesia in horses than current clinical protocols. Objective: Administration of gabapentin at 40 and 120 mg/kg PO q 12 h for 14 days will not alter serum biochemistry findings or cause adverse effects. Our objectives were to evaluate the effect of gabapentin on serum biochemistry, physical examination, and plasma Gabapentin, as administered here, did not improve subjective or objective measures of lameness in horses with chronic thoracic limb musculoskeletal pain. Although subjective evaluation identified an improvement in lameness with treatment GF, it was not different from that observed with treatment F. Gabapentin, paracetamol and t-TUCB Gabapentin has been used extensively for the treatment of pain of nerve origin in horses, and, more recently, for the treatment of other painful conditions including laminitis. This review aimed to clarify gabapentin use and pharmacokinetic aspects to promote conscious use in dogs, cats, and horses. In dogs, gabapentin was beneficial in the treatment of epilepsy, as well as chronic, neuropathic, and post-operative pain, as well as anxiety. This review aimed to clarify gabapentin use and pharmacokinetic aspects to promote conscious use in dogs, cats, and horses. In dogs, gabapentin was beneficial in the treatment of epilepsy, as well as chronic, neuropathic, and post-operative pain, as well as anxiety. This type of pain may be seen in horses with chronic arthritis and chronic laminitis. Gabapentin (2.5 to 10 mg/kg PO q12h) may be used to treat neuropathic pain. The United States Equine Federation (USEF) has a 14-day withholding period for gabapentin. Pharmacologic Pain Management Gabapentin has been used in horses for many years, and is often prescribed as adjunct therapy for horses with pain rising from laminitis, particularly as part of a multimodal approach to pain management. 2 In the recent study, researchers used 14 horses with long-lasting forelimb lameness to evaluate the pain-relieving effects of oral gabapentin. What does gabapentin do for a horse? Higher oral dosing and longer treatment regimens of gabapentin may be indicated for the treatment of chronic musculoskeletal pain in horses. How much gabapentin can you give a horse? Conclusion and clinical importance: Our results suggest that horses tolerate gabapentin up to 120 mg/kg PO q 12 h for 14 days. The analgesic effect of the dosage regimens Paracetamol and gabapentin are attractive for use in horses because they have an oral route of administration, low cost and few perceived side effects. This review discusses the published evidence regarding the likely efficacy of these drugs, and how best to maximise their use. All horses tolerated the PO administration of gabapentin, and no evidence of side effect (e.g. somnolence, depression, sedation, or ataxia) of the drug at either dose (5 or 10 mg/kg bwt) was observed. No significant reduction in lameness level was observed while receiving either gabapentin dose when compared with the placebo group. Further studies are necessary to determine effective plasma concentration and length of treatment period after PO administered gabapentin for analgesia in horses with chronic lameness. Hi, I’ve got a guy on 24/7 stall rest who’s just starting on gabapentin. My vet hasn’t seen any side effects from it but I’d swear I read that it can cause horses to be quieter (not that I can figure out where I read that - maybe I’m confusing it with something else). The horse is an unbelievable saint about stall rest, but is starting to feel better, so I wouldn’t mind a little However, Caldwell et al. (2015) reported no subjective improvement in lameness in horses administered gabapentin at oral doses of 5 and 10 mg kge 1 three times daily for 14 days. A pharmacokinetic study indicated poor oral bioavailability ( 16%) of gabapentin in horses (Terry et al. 2010) compared with reported values in humans (29 83%), e
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