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Symptoms consistent with bruxism are a common chief complaint in dental practice. The authors describe a case of bruxism likely induced by the antidepressant venlafaxine and successfully treated with gabapentin. Bruxism is reported as a side effect among people who take Gabapentin (gabapentin), especially for people who are female, 60+ old, have been taking the drug for 1 - 6 months also take Celebrex, and have Narcolepsy. The above data suggest that the addition of buspirone 5–10 mg up to 3 times daily may be an effective first-line option for alleviating antidepressant-associated bruxism, particularly in patients who may not tolerate dose reduction or medication cessation. Despite numerous case reports, the evidence for treatment of bruxism is still low. Different treatment modalities (behavioral techniques, intraoral devices, medications, and contingent electrical stimulation) have been applied. A clinical evaluation is needed to differentiate between awake bruxism and sleep bruxism and rule out any medical disorder or medication that could be behind its The term bruxism is said to come from the Greek word "brychein," which means "to grind or gnash the opposing rows of upper and lower molar teeth." Per recent classification of sleep disorders, bruxism is defined as a sleep-related movement disorder. The Glossary of Prosthodontic Terms (GPT-8) defines bruxism as parafunctional tooth grinding habit consisting of involuntary rhythmic or spasmodic Abstract Bruxism is a repetitive jaw‐muscle activity characterised by clenching or grinding of the teeth and/or by bracing or thrusting of the mandible. It can occur during sleep, indicated as sleep bruxism, or during wakefulness, indicated as awake bruxism. Exogenous risk indicators of sleep bruxism and/or awake bruxism are, among others, medications and addictive substances, whereas also Nocturnal bruxism has been reported with venlafaxine, a serotonin/noradrenaline reuptake inhibitor, which responded to gabapentin (Brown & Hong, 1999), as well as three selective serotonin reuptake inhibitors (SSRIs), paroxetine (Romanelli et al, 1996), fluoxetine and setraline (Ellison & Stanziani, 1993). We summarize the clinical features and treatment of antidepressant-associated bruxism and associated jaw pain through a systematic review of case reports. Antidepressant-associated bruxism may occur in pediatric and adult patients, most commonly among female patients. Patients may develop symptoms with short-term and long-term antidepressant use. Gabapentin is a neutral gamma-aminobutyric acid (GABA) analog, which, in general, has few side effects and, overall, appears to be a safe, easy-to-titrate, well-tolerated drug in patients with seizure disorders. Its use in other neuropsychiat-ric disorders is currently under investigation. Bruxism is a repetitive jaw-muscle activity characterised by clenching or grinding of the teeth and/or by bracing or thrusting of the mandible. It can occur during sleep, indicated as sleep bruxism, Oh, interesting! I've been taking a pretty low dose of gabapentin for years for back nerve pain. It makes me really sleepy and foggy, so I've never agreed to increase. Is the plan for you to take the high gabapentin dose short term or long term? I'm wondering if I could up mine for a while just to help with clenching. Gabapentin may offer promise in the treatment of this condition. On the basis of this case and the available literature, the authors conclude that bruxism secondary to antidepressant therapy may be common. Thus, dentists should inquire about the use of these medications in patients who have bruxism. Only one study have compared occlusal splints versus a medication doses gabapentin, and found that both treatments reduced similarly the muscle activity associated with sleep bruxism after 2 month of therapy [25]. Temporomandibular disorders affect between 5% and 12% of the population and present with symptoms such as headache, bruxism, pain at the temporomandibular joint, jaw popping or clicking, neck pain Conclusions: If a patient with bruxism is responding to an antidepressant then trial of occlusal guard and medication dose reduction should be a first step. If lowering the dose of antidepressant fails, addition of buspirone should be considered next followed by other medication options. Abstract We describe a case of sertraline-induced bruxism. Different medications were tried to manage bruxism, including buspirone, gabapentin, quetiapine, and clonazepam. Quetiapine gave the best result in treating bruxism in our patient, but its side effects, mainly weight gain, were intolerable. The dosage of Gabapentin prescribed by doctors to treat the sleep disorder insomnia and improve overall sleep quality is generally between 100-400 mg. Gabapentin therapy was begun (300 mg at night) for insomnia and anxiety. The patient was advised to consult with a dentist if the bruxism continued. At his next appointment four weeks later, the patient reported that the anxiety, tremor, insomnia and bruxism all had completely resolved within one to two days of starting gabapentin therapy. DEFINITION Bruxism is defined as repetitive jaw-muscle activity characterized by grinding or clenching of the teeth [1] and/or by bracing or thrusting of the mandible [2]. Bruxism is most common during sleep, when it is referred to as sleep-related bruxism. This case also suggests that gabapentin may be a useful treatment for patients with antidepressant-induced bruxism. Gabapentin has been approved by the Food and Drug Administration as add-on therapy for control of seizures and is administered in divided doses totaling or exceeding 3,600 mg per day.8,9 Although the mechanism of action of
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