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DESCRIPTION Neurontin® (gabapentin) Capsules, Neurontin (gabapentin) Tablets, and Neurontin (gabapentin) Oral Solution are supplied as imprinted hard shell capsules containing 100 mg, 300 mg, and 400 mg of gabapentin, elliptical film-coated tablets containing 600 mg and 800 mg of gabapentin or an oral solution containing 250 mg/5 mL of gabapentin. Medscape - Seizure dosing for Neurontin, Gralise (gabapentin), frequency-based adverse effects, comprehensive interactions, contraindications, pregnancy & lactation schedules, and cost information. Due to the primarily renal excretion of GABAPENTIN, the following dosage adjustments are recommended for elderly patients with declining renal function, patients with renal impairment and patients undergoing hemodialysis (see DOSAGE AND ADMINISTRATION, Dosing Considerations; ACTION AND CLINICAL PHARMACOLOGY, Special Populations and Conditions). 2 DOSAGE AND ADMINISTRATION 2.1 Postherpetic Neuralgia - Once-daily gabapentin tablets are not interchangeable with other gabapentin products. Titrate gabapentin tablet to an 1,800 mg dose taken orally once daily with the 3 DOSAGE FORMS AND STRENGTHS 4 CONTRAINDICATIONS Learn about gabapentin dosages based on treatment, medical condition, children, and more with GoodRx. U.S.-based MDs, DOs, NPs and PAs in full-time patient practice can register for free access to the Prescribers’ Digital Reference on PDR.net. PDR.net is to be used only as a reference aid, it is not intended to be a substitute for the exercise of professional judgement. DESCRIPTION Neurontin® (gabapentin) Capsules, Neurontin (gabapentin) Tablets, and Neurontin (gabapentin) Oral Solution are supplied as imprinted hard shell capsules containing 100 mg, 300 mg, and 400 mg of gabapentin, elliptical film-coated tablets containing 600 mg and 800 mg of gabapentin or an oral solution containing 250 mg/5 mL of gabapentin. U.S.-based MDs, DOs, NPs and PAs in full-time patient practice can register for free access to the Prescribers’ Digital Reference on PDR.net. PDR.net is to be used only as a reference aid, it is not intended to be a substitute for the exercise of professional judgement. You should confirm the information on the PDR.net site through independent sources and seek other professional guidance in Gabapentin has been associated with serious, life-threatening, or fatal respiratory depression when co-administered with central nervous system (CNS) depressants, including opioids, or when there is an underlying respiratory impairment. DOSAGE AND ADMINISTRATION 4.1 Dosing Considerations Because GABAPENTIN is eliminated solely by renal excretion, dosage adjustments are recommended for patients with renal impairment (including elderly patients with declining renal function) and patients undergoing hemodialysis. The dose of gabapentin tablets should be adjusted in patients with reduced renal function, according to Table 2. Patients with reduced renal function must initiate gabapentin tablets at a daily dose of 300 mg. Gabapentin tablets should be titrated following the schedule outlined in Table 1. Daily dosing in patients with reduced renal function must be individualized based on tolerability and Prescribers’ Digital Reference ® PDR Drug Information Fully searchable Fully digital Trusted by generations of healthcare providers, PDR.net supports prescribing decisions and patient adherence to improve health. Gabapentin is an anti-epileptic drug, also called an anticonvulsant. It is used to treat some types of seizures and nerve pain caused by shingles. 2.1 Dosage for Postherpetic Neuralgia In adults with postherpetic neuralgia, NEURONTIN may be initiated on Day 1 as a single 300 mg dose, on Day 2 as 600 mg/day (300 mg two times a day), and on Day 3 as 900 mg/day (300 mg three times a day). The dose can subsequently be titrated up as needed for pain relief to a dose of 1800 mg/day (600 mg three times a day). In clinical studies, efficacy was An additional gabapentin 1,200 mg/day dosage group (N=52) provided dose-response data. A statistically significant difference in responder rate was seen in the gabapentin 900 mg/day group (22%) compared to that in the placebo group (10%). Patients 12 years of Age and above The starting dose is 300 mg three times a day. The recommended maintenance dose of gabapentin capsules is 300 mg to 600 mg three times a day. Dosages up to 2400 mg/day have been well tolerated in long-term clinical studies. Doses of 3600 mg/day have also been administered to a small number of patients for a relatively short duration, and have been well Pediatric Adjuvant Rx Dosing Table (Recommended starting doses < 50kg) Additional options to consider for constipation refractory to above: glycerin suppository, fleet enema, milk of magnesia, magnesium citrate, lubiprostone Neurontin (gabapentin) is used to treat seizures and nerve pain caused by the herpes virus. Includes Neurontin side effects, interactions and indications. Detailed Gabapentin dosage information for adults and children. Includes dosages for Restless Legs Syndrome, Epilepsy and Postherpetic Neuralgia; plus renal, liver and dialysis adjustments. 2.1 Dosage for Postherpetic Neuralgia In adults with postherpetic neuralgia, NEURONTIN may be initiated on Day 1 as a single 300 mg dose, on Day 2 as 600 mg/day (300 mg two times a day), and on Day 3 as 900 mg/day (300 mg three times a day). The dose can subsequently be titrated up as needed for pain relief to a dose of 1800 mg/day (600 mg three times a day). In clinical studies, efficacy was
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