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Gabapentin is commonly administered to dogs and cats to treat chronic and neuropathic pain (Beckman 2013). Furthermore, pain reduction following orally administered gabapentin in horses has been described in several clinical reports (Davis et al. 2007; Dutton et al. 2009; Readford et al. 2013). No signi cant reduc-fi tion in lameness level was observed while receiving either gabapentin dose when compared with the placebo group. Further studies are necessary to determine effective plasma concentration and length of treatment period after PO administered gabapentin for analgesia in horses with chronic lameness. 2015 Elsevier Inc. All horses tolerated the PO administration of gabapentin, and no evidence of side effect (e.g. somnolence, depression, sedation, or ataxia) of the drug at either dose (5 or 10 mg/kg bwt) was observed. The repeated administration of high doses of gabapentin may provide better analgesia in horses than current clinical protocols. Objective: Administration of gabapentin at 40 and 120 mg/kg PO q 12 h for 14 days will not alter serum biochemistry findings or cause adverse effects. Our objectives were to evaluate the effect of gabapentin on serum biochemistry, physical examination, and plasma What does gabapentin do for a horse? Higher oral dosing and longer treatment regimens of gabapentin may be indicated for the treatment of chronic musculoskeletal pain in horses. How much gabapentin can you give a horse? Conclusion and clinical importance: Our results suggest that horses tolerate gabapentin up to 120 mg/kg PO q 12 h for 14 days. The analgesic effect of the dosage regimens Gabapentin, as administered here, did not improve subjective or objective measures of lameness in horses with chronic thoracic limb musculoskeletal pain. Although subjective evaluation identified an improvement in lameness with treatment GF, it was not different from that observed with treatment F. Paracetamol and gabapentin are attractive for use in horses because they have an oral route of administration, low cost and few perceived side effects. This review discusses the published evidence regarding the likely efficacy of these drugs, and how best to maximise their use. 1. INTRODUCTION Limited scientific information exists regarding the effective and safe dosing of gabapentin in horses. Based on clinical experience and anecdotal reporting, 1 the most commonly used dosage of gabapentin is either 10 or 20 mg/kg 2 , 3 which by itself is often ineffective at controlling pain from laminitis or osteoarthritis. Higher dosages or more frequent administration may Simple math is required to calculate the dose of a particular medication for administration to horses and other equines. This article reviews the forms of equine medications, and the calculations that you can use to get the dose right! Equine Gabapentin Dose is a powerful medication that effectively manages chronic pain, neuropathic pain, and seizures in horses. It provides fast and long-lasting relief, allowing your horse to regain its vitality and quality of life. Davis et al [9] found that gabapentin administered at a dose of 2.5 mg/kg bwt PO every 8 hours to a pregnant draft horse was effective in the treatment of femoral neuropathy after colic surgery. This review aimed to clarify gabapentin use and pharmacokinetic aspects to promote conscious use in dogs, cats, and horses. In dogs, gabapentin was beneficial in the treatment of epilepsy, as well as chronic, neuropathic, and post-operative pain, as well as anxiety. Our results suggest that horses tolerate gabapentin up to 120 mg/kg PO q 12 h for 14 days. The analgesic effect of the dosage regimens evaluated in our study warrants further research. To evaluate the analgesic effects of orally administered gabapentin on horses with chronic thoracic limb lameness. Gabapentin, paracetamol and t-TUCB Gabapentin has been used extensively for the treatment of pain of nerve origin in horses, and, more recently, for the treatment of other painful conditions including laminitis. View peer-reviewed research and journal articles on Gabapentin for horses. Explore its effects, therapeutic uses, and safety in equine medicine. Limited scientific information exists regarding the effective and safe dosing of gabapentin in horses. Based on clinical experience and anecdotal reporting,1 the most commonly used dosage of gabapentin is either 10 or 20 mg/kg2,3which by itself is often inef-fective at controlling pain from laminitis or osteoarthritis. Gabapentin has a relatively low bioavailability, but no apparent adverse effects following oral administration in horses 75, 76. Further work is needed to assess the clinical effect of gabapentin more objectively in horses with clinical pain. This textbook includes basic principles of large animal surgery and anesthesia, how to apply those principles to cases and situations, and discover ways of finding answers when you don’t remember the information, are presented with cases that aren’t “textbook” and/or things don’t go as planned. Gabapentin has been used in horses for many years, and is often prescribed as adjunct therapy for horses with pain rising from laminitis, particularly as part of a multimodal approach to pain management. 2 In the recent study, researchers used 14 horses with long-lasting forelimb lameness to evaluate the pain-relieving effects of oral gabapentin.
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