Gallery
Photos from events, contest for the best costume, videos from master classes.
 |  |
 |  |
 |  |
 |  |
 |  |
 |  |
Though Gabapentin remains well established as a first-line treatment for diabetic neuropathy, 14,15 few randomized control studies have examined the utility of the drug in corneal neuropathic pain. 16 Ongun et al. showed a decrease in patient reported pain in a cohort of patients with chronic corneal neuropathic pain and dry eye disease treated Studies show MSO may benefit from gabapentin or memantine. Opsoclonus and ocular flutter may be reduced with propranolol, clonazepam, gabapentin, topiramate, levetiracetam, or ethosuximide. [4] Surgery Deep brain stimulation (DBS) may be considered for surgical treatment of saccadic intrusions. Disease Entity Disease Oculopalatal tremor (OPT) (also known as oculopalatal myoclonus or pharyngo-laryngo-diaphragmatic myoclonus) is an acquired syndrome of continuous and rhythmical movements of the soft palate combined with pendular nystagmus. It occurs after injury to the brainstem or cerebellar regions. The concurrent nystagmus can be synchronous or asynchronous, and it may be seen as a Superior Oblique Myokymia (SOM) is a rare condition, characterized by episodes of sudden, rhythmic, monocular contractions of the superior oblique muscle. Based on pathophysiological hypotheses, pharmacological treatments for APN have been examined in treatment trials, leading to the proposal of gabapentin or memantine as effective agents (5–9). In these studies, the efficacy of memantine and gabapentin was based on objective ocular motor measures, including nystagmus amplitude and/or velocity. Oral gabapentin is a first-line treatment for chronic systemic neuropathic pain. Although it has been used for ocular discomfort after refractive surgery and in severe, painful dry eye syndrome (DES), Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat neuropathic pain and also for partial seizures [10][7] of epilepsy. Gabapentin (GBT) is a structural analog of gamma-amino butyric acid that has been used by systemic administration to provide pain relief in glaucomatous patients. We have already shown in a rabbit model system that its topic administration as eye drops has anti-inflammatory properties. Retinal toxicity or abnormality can be induced by usage of various medications. In the majority of instances, toxicity is reversible following discontinuation of the inciting drug. However, permanent or progressive vision loss may occur in a few instances even despite drug cessation. This page will review the toxicities most likely to be encountered in common clinical practice. Overview of etiology, classification, clinical presentation, and treatment of varicella zoster stromal keratitis and endotheliitis. Chronic Pain Drug May Cause Angle-closure Patients who took gabapentin the year prior to diagnosis were at higher risk than current users. If your patients have taken gabapentin to manage chronic pain or other conditions, they may have a higher chance of developing acute angle-closure glaucoma, Canadian researchers report. Gabapentin Pharmacokinetics and Effects on Corneal Sensitivity and Lacrimation The distribution of GBT eye drops (2% in PBS) has been evaluated in aqueous humor, cornea and conjunctiva. Disease Entity Definition Ocular neuropathic pain, also referred to as corneal neuropathic pain, is a condition where corneal pain is seen in response to normally non-painful stimuli. This results from repeated direct damage to corneal nerves. Aberrant regeneration with upregulation of nociceptors responsible for processing of painful stimuli leads to hyper-responsivity and increased Download PDF The gabapentinoids gabapentin and pregabalin are among the most commonly prescribed drugs in North America. Now, researchers have found an association between gabapentin and the incidence of acute angle-closure glaucoma (AAG). 1 A similar association was not found for pregabalin. Both drugs are approved to treat epilepsy and selected chronic pain conditions and are widely used In this study, the gabapentin group felt significantly less pain on the morning of the second post-operative day only [1]. Oral analgesics can be used as a “rescue medication” [2] if topical eye drops are not providing adequate analgesia for post-operative pain. Further studies about the mechanism and frequency of macular edema after gabapentin are required. In summary, we report macular edema occurring in a male patient receiving gabapentin therapy for postherpetic neuralgia treatment. The macular edema improved after discontinuing the use of the drug. Disease Inferior Oblique Myokymia (IOM) is a rare disorder, characterized by intermittent episodes of monocular, high-frequency, low-amplitude contractions of the inferior oblique muscle [1]. Patients experience excyclotorsion induced by looking up and out [1]. Transient vertical oscillopsia and excyclotorsion may manifest spontaneously as well [2]. Etiology The etiology of IOM is idiopathic Disease Entity ICD10 - G23.1 Disease Progressive supranuclear palsy (PSP) or Steele-Richardson-Olszewski syndrome is characterized by a progressive supranuclear ophthalmoplegia typically vertical but in particular downward limitation of eye movement. There is often associated loss of balance due to degeneration of neurons in the brainstem and basal ganglia. [1] PSP is recognized as a tauopathy Disease Ocular neuromyotonia (ONM) is a rare ocular motor disorder characterized by intermittent, tonic spasms of one or more of the extraocular muscles, resulting in strabismus and paroxysmal diplopia [1]. Episodes of ONM are caused by involuntary neural discharges and delayed muscle relaxation due to a damaged nerve [1] [2]. Etiology ONM commonly occurs with the history of cranial radiation Epidemiology and Risk factors Glaucoma is a form of optic neuropathy. It is usually associated with intra-ocular pressure (IOP) abnormalities, thinning of the retinal nerve fiber layer (RNFL), characteristic visual field loss, and may be categorized as open or closed angle based on the status of the iridocorneal angle. Several topical and systemic medications may induce acute angle closure
Articles and news, personal stories, interviews with experts.
Photos from events, contest for the best costume, videos from master classes.
| |
| |
| |
| |
| |
| |