The SmPC of gabapentin mentions blood glucose fluctuations in diabetic patients as a potential adverse drug reaction with unknown frequency [1]. Abstract Gabapentin can cause mild disorders of blood glucose due to an unknown mechanism of action. Because of the lack of data in the medical literature, it is dificult to define the true incidence or causality of gabapentin-induced hyperglycemia. Recent research suggests that this may not occur. _________________ Because of the constantly changing nature of the U.S. prescription and OTC drug marketplace, this list may not reflect the full range of drugs that may impact blood glucose levels. The information contained in this document is intended as an educational aid only. It is not intended as medical advice for individual conditions Objective: A possible case of gabapentin-induced mild hyperglycemia is reported. Case Summary: A 63-year-old Caucasian gentleman was treated in a pharmacist-run pharmacotherapy clinic for type 2 diabetes management. His comorbidities included type 2 diabetes mellitus, hypertension, dyslipidemia, coronary artery disease, peripheral vascular disease, Barrett's esophagus, chronic back pain, and CONCLUSIONS: Hypoglycemia is a rarely acknowledged adverse effect of gabapentin overdose and requires urgent intervention as it could be initially resistant to simple glucose replacement and may lead to serious consequences. In this case, blood glucose levels responded only to high concentration dextrose infusion (D10) with concomitant tube feeds. Gabapentin has not been reported to raise blood sugar, however it would be best to consult a pharmacist/doc who would have prescribed the med. Take care, be well & safe! Although blood glucose fluctuations are a possible adverse drug reaction (ADR) of gabapentin 1, hypoglycaemia in relation to this drug was found in just one publication 3. We received six cases of (severe) hypoglycaemia in both diabetic and non-diabetic patients exposed to gabapentin, which occurred between July 2002 and July 2012. From a search of the medical literature, 2 articles speak to the effect of gabapentin on blood glucose levels. Backonja and colleagues 5 conducted a randomized, double-blind, placebo-controlled, parallel arm, multicenter study to determine the efficacy and safety of gabapentin as monotherapy for diabetes neuropathy. Do you take Gabapentin and are concerned about Hyperglycemia? eHealthMe's data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Check whether Hyperglycemia is associated with a drug or a condition. Hi.. yes..High Blood Sugar rare side effects of Neurontin.. please consult with your health care provider as soon as possible.. good luck. From statins and antidepressants to antibiotics, here’s a list of drugs that may raise your blood sugar — and what you can do about it. Gabapentin is an anticonvulsant medication prescribed for a variety of conditions. Learn about its uses, side effects, and what you should know if you've been prescribed this medication. Do you take Gabapentin and are concerned about Blood glucose increased? eHealthMe's data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Check whether Blood glucose increased is associated with a drug or a condition. Postmarketing research of gabapentin has shown fluctuation of blood glucose levels. Ask your doctor to evaluate your blood glucose levels for hypoglycemia. He/she might want to adjust your dose of gabapentin, or send you to a dietician to establish a special diet to control the low blood sugar if your glucose is not dropping too severely. K Food and exercise aren’t the only things that can raise your blood sugar. Learn about the effect of non-diabetes medicines. Therefore, while gabapentin itself may not directly increase blood sugar levels, changes in body weight associated with its use could potentially have an impact on glucose metabolism. Research Findings on Gabapentin and Blood Sugar Several studies have explored the relationship between gabapentin and metabolic changes. Do you take Gabapentin and are concerned about Blood glucose abnormal? eHealthMe's data-driven phase IV clinical trials have been referenced on 800+ peer-reviewed medical publications including The Lancet, Mayo Clinic Proceedings, and Nature. Check whether Blood glucose abnormal is associated with a drug or a condition. Purpose: Gabapentin is an analog of gamma-aminobutyric acid (GABA), but its complete mechanism is not well understood. Common adverse effects from gabapentin include somnolence, sedation, and dizziness. Hyperglycemia is listed as a possible adverse drug reaction in the labeling. Case reports describe hypoglycemia in patients with diabetes, peritoneal dialysis, and/or incomplete medication
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