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287 medications are known to interact with lamotrigine. Includes gabapentin, sertraline, metformin. Lamotrigine (Lamictal) is a medication taken for seizures and bipolar disorder. Learn which drugs interact with lamotrigine, possible side effects, and more. A Minor Drug Interaction exists between Lamictal and Neurontin. View detailed information regarding this drug interaction. A Minor Drug Interaction exists between gabapentin and lamotrigine. View detailed information regarding this drug interaction. Lamictal Interactions There are 287 drugs known to interact with Lamictal (lamotrigine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 38 are major, 237 are moderate, and 12 are minor. The pharmacokinetics, efficacy, and adverse effects of gabapentin and lamotrigine, two new antiepileptic drugs (AEDs), are reviewed. Gabapentin and lamotrigine are promising advances in the treatment of epilepsy, which has not been satisfactorily controlled by available agents in 25-41% of patients. Gabapentin and lamotrigine are two new anticonvulsants that appear to have mood stabilizing properties. The authors review the pharmacology, pharmacokinetics, and adverse effects of these two agents and review the promising preliminary findings concerning their efficacy as mood stabilizers. Cautions with other medicines Some medicines and lamotrigine can affect each other and increase the chances of side effects. Your doctor may need to change your dose of lamotrigine. Check with your pharmacist or doctor if you're taking: other medicines used to treat epilepsy, such as carbamazepine, felbamate, gabapentin, levetiracetam, oxcarbazepine, phenobarbital, phenytoin, pregabalin The following applies to the ingredients: Gabapentin and Lamotrigine (found in Lamictal) Professional Content Lamotrigine may increase the plasma concentrations of renally excreted drugs that are substrates of OCT 2. Lamotrigine inhibits OCT 2 in vitro. The clinical significance is unknown. A Minor Drug Interaction exists between gabapentin and Lamictal. View detailed information regarding this drug interaction. Compare Lamotrigine and Gabapentin for epilepsy treatment. Which medication is more effective? Learn about their benefits, side effects, and usage in this informative guide. We compare the side effects and drug effectiveness of Lamotrigine and Gabapentin. The study is created by eHealthMe based on 572,644 reports. A phase IV clinical study of FDA data: drug interactions are found among 33 people who take Neurontin (gabapentin) and Lamictal xr (lamotrigine). The utility of gabapentin and lamotrigine for the treatment of bipolar disorder is reviewed. Bipolar disorder is characterized by extreme mood fluctuations, including mania, hypomania, depression, and mixed episodes. Extrapolation of postulated mechanisms of anticonvulsant activity in bipolar disord A phase IV clinical study of FDA data: drug interactions are found among 4,920 people who take Gabapentin (gabapentin) and Lamotrigine (lamotrigine). Newer antiepileptic drugs may control seizures more effectively, but their significant potential for serious side effects requires a thorough knowledge of the drugs and careful consideration of Compare Gabapentin vs Lamotrigine head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Gabapentin is eliminated unchanged by the kidney for 100%. Lamotrigine is principally metabolised by UDP-glucuronosyltransferases. This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects. [4] Lithium and gabapentin. Gabapentin is currently being studied as a treatment for bipolar disorder, and there have been favorable reports regarding its potential as a mood stabilizer (82, 83). The advantages of gabapentin include the lack of interactions with other drugs in the cytochrome P450 system and the lack of protein binding (84). A phase IV clinical study of FDA data: drug interactions are found among 2,876 people who take Lamictal (lamotrigine) and Gabapentin (gabapentin).
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