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Abstract In the past, interactions between drugs and vitamin D have received only little or no attention in the health care practices. However, since more and more drugs are used for the treatment of patients, this topic is increasingly relevant. Several drugs can interfere with the vitamin D and bone metabolism. Drugs that activate the pregnane X receptor can disrupt vitamin D metabolism and Some potential interactions to be aware of include: Increased sedation: Both Vitamin D and Gabapentin can cause drowsiness, so combining them may intensify this side effect. Altered medication effectiveness: Gabapentin may interfere with the absorption of Vitamin D, potentially reducing its effectiveness. Things to avoid while taking gabapentin include alcohol, CNS depressants, antacids, and caffeine. Learn how the side effects may be exacerbated by these interactions. Understanding the interaction between vitamin D and gabapentin is crucial for safe supplementation. Both gabapentin and Vitamin D have been studied for their effects on conditions such as neuropathic pain and mood disorders. Some anecdotal evidence suggests that maintaining optimal Vitamin D levels may help improve symptoms in individuals taking gabapentin for nerve pain. A phase IV clinical study of FDA data: drug interactions are found among 3,293 people who take Gabapentin (gabapentin) and Vitamin d3 (cholecalciferol). Research indicates that taking vitamin D alongside gabapentin may alter how the body metabolizes this medication. This interaction could potentially enhance the side effects of gabapentin, such as dizziness, drowsiness, or cognitive impairment. Vitamin D is an essential vitamin that may interact with other medications and supplements, such as statins, thiazide diuretics, and magnesium. Individuals on long-term multiple anticonvulsant therapy may develop below-normal blood levels of calcium, which may be related to drug-induced vitamin D deficiency. Two infants born to women taking high doses of phenytoin and phenobarbital while pregnant developed jitteriness and tetany (a syndrome characterized by muscle twitches) cramps, and spasm during the first two weeks of life A phase IV clinical study of FDA data: drug interactions are found among 6,767 people who take Gabapentin (gabapentin) and Multivitamin (ascorbic acid; biotin; cyanocobalamin; dexpanthenol; ergocalciferol; folic acid; niacinamide; pyridoxine hydrochloride; riboflavin phosphate sodium; thiamine hydrochloride; vitamin a; vitamin e). View drug interactions between gabapentin and Vitamins. These medicines may also interact with certain foods or diseases. Vitamin D3 Interactions There are 91 drugs known to interact with Vitamin D3 (cholecalciferol), along with 5 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 11 are major, 79 are moderate, and 1 is minor. Taking herbal remedies and supplements that can make you feel dizzy or drowsy while you're taking gabapentin could make these side effects worse. Gabapentin can intensify the highs of recreational drugs like cannabis and heroin. Learn about the potential interactions between vitamin D and gabapentin, including whether it is safe to take them together and any potential risks or benefits. View drug interactions between gabapentin and Vitamin D3. These medicines may also interact with certain foods or diseases. I also take prednisone, tramadol, gabapentin, methotrexate and leucovorin. Could one of these drugs interfere with vitamin D absorption? Evidence-based interaction details between Gabapentin (brand name (s): Neurontin, Gralise) and Vitamin D, including interaction severity and how likely the interaction is to occur. The purpose of this systematic review is to determine the extent to which drugs affect vitamin D status (by altering absorption, metabolism, or excretion of vitamin D), or the extent to which vitamin D alters drug absorption and metabolism, activity or toxicity. Drug interactions are reported among people who take Gabapentin (gabapentin) and Vitamin d (ergocalciferol). Common drug interactions include chronic kidney disease among females and fatigue among males. View drug interactions between Neurontin and Vitamin D3. These medicines may also interact with certain foods or diseases.
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