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Whether you’re already taking gabapentin for an anxiety disorder or are curious if you might benefit from it, you may be wondering how effective it is, how it works, and if there are side effects. Here we’ll cover everything you need to know about gabapentin for anxiety. What is Gabapentin? Outpatient prescription of gabapentin for FDA-approved indications (i.e., partial-onset seizures and postherpetic neuralgia) was less than 1%, and depression and anxiety disorders were the most frequent psychiatric diagnoses among off-label users. Gabapentin may offer several benefits for individuals managing anxiety, particularly when traditional treatments aren’t effective or well-tolerated. Though it’s prescribed off-label, gabapentin helps anxiety by: Reduced symptoms of social anxiety and phobias: Research has shown Gabapentin can help ease symptoms in people with social phobia. Gabapentin is an off-label medication that may help with some types of situational anxiety, but not generalized anxiety disorder. Learn how gabapentin works, what side effects and risks it may have, and how it compares to Xanax. Adding gabapentin to fluoxetine in the treatment of OCD seems to shorten the time to onset of fluoxetine's anti-obsessive effect without a significant increase in adverse effects. Learn about gabapentin for anxiety: its uses, side effects, and how it can be combined with other treatments. Abstract Objective: This article reviews evidence-based psychiatric uses of gabapentin, along with associated risks. Method of Research: An extensive literature review was conducted, primarily of articles searchable in PubMed, relating to psychiatric uses, safety, and adverse effects of gabapentin. Results: Evidence supports gabapentin as a treatment for alcohol withdrawal and alcohol use Explore Gabapentin (Neurontin) for anxiety relief: typical dosage guidelines, side effects, and its effectiveness in managing anxiety. Results: Gabapentin may have benefit for some anxiety disorders, although there are no studies for generalized anxiety disorder. Gabapentin has less likely benefit adjunctively for bipolar disorder. Gabapentin has clearer efficacy for alcohol craving and withdrawal symptoms and may have a role in adjunctive treatment of opioid dependence. The present pattern of results suggests that glutamatergic medications such as gabapentin and memantine adjuvant to a standard treatment with an SSRI have no additional positive impact on patients with OCD, as measured with the Y-BOCS. Additionally, side-effects were reported. Future studies should This article reviews evidence-based psychiatric uses of gabapentin, along with associated risks. An extensive literature review was conducted, primarily of articles searchable in PubMed, relating to psychiatric uses, safety, and adverse effects of This review will focus on the comparative properties of gabapentin and pregabalin, specifically the available evidence on their use in the treatment of primary anxiety disorders — GAD, social anxiety disorder, panic disorder, and obsessive-compulsive disorder. Explore how gabapentin can help manage anxiety and stress, its effects, research findings, and important considerations for use. Pregabalin is currently ap-proved for the treatment of generalized anxiety disor-der (GAD) by the European Medicines Agency, but not by the U.S. FDA. Results: Evidence supports gabapentin as a treatment for alcohol withdrawal and alcohol use disorder. There is sufficient evidence to consider gabapentin as a third-line treatment for social anxiety disorder and severe panic disorder. Gabapentin does appear to provide benefit for some anxiety disorders, although randomized controlled trials have been limited to social phobia, anxiety in breast cancer, and perioperative anxiety. The interaction between glutamatergic and GABAergic systems has been considered to improve the symptoms of OCD, and gabapentin has been shown to be efficient in reducing the symptoms of anxiety; therefore, we thought that gabapentin might be useful in the treatment of OCD as add-on medication. Gabapentin can also cause mood fluctuations, and increased depression and anxiety, which can worsen OCD symptoms in some people. Withdrawing from gabapentin can also trigger mood disorders, moodiness, and other mental health conditions, like anxiety and suicidal ideation (thoughts and attempts). Our preliminary observations suggest a role for gabapentin as monotherapy or for adjunctive use in patients with panic disorder or generalized anxiety disorder. The promising preliminary results encourage further clinical exploration and systematic study of gabapentin for the treatment of anxiety disorders.
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