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Olanzapine, sold under the brand name Zyprexa among others, is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder. [12] It is also sometimes used off-label for treatment of chemotherapy-induced nausea and vomiting [13] and as an appetite stimulant. [14] For schizophrenia, it can be used for both new-onset disease and long-term maintenance. [12] It is taken by Gabapentin was added to ongoing antipsychotic treatment with olanzapine or risperidone for eight weeks. The primary outcome measure was the Positive and Negative Syndrome Scale (PANSS). Other scales included the Calgary Depression Scale (CDSS) and the Abnormal Involuntary Movement Scale (AIMS). Find patient medical information for Olanzapine (Zyprexa) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings Drug interactions are reported among people who take Olanzapine (olanzapine) and Gabapentin (gabapentin). Common drug interactions include suicide attempt among females and drug ineffective among males. Carbamazepine decreases the plasma concentrations of both risperidone and its active metabolite. It also decreases concentrations of olanzapine, clozapine, ziprasidone, haloperidol, zuclopenthixol, flupenthixol and probably chlorpromazine and fluphenazine. Olanzapine side effects Olanzapine may cause serious side effects such as an increased risk of death or stroke in elderly patients with dementia, a higher risk of suicide when taken with fluoxetine, metabolic changes, tardive dyskinesia, low blood pressure, and blood cell disorders. See the warnings below for a full list of serious side effects. Olanzapine: learn about side effects, dosage, special precautions, and more on MedlinePlus Description Olanzapine is used to treat schizophrenia. It may also be used alone or with other medicines (eg, lithium or valproate) to treat mania or mixed episodes that is part of bipolar disorder (manic-depressive illness). Olanzapine may also be used together with fluoxetine to treat depression that is a part of bipolar disorder, and depression in patients who received other antidepressants Detailed Olanzapine dosage information for adults, the elderly and children. Includes dosages for Depression, Bipolar Disorder, Schizophrenia and more; plus renal, liver and dialysis adjustments. 667 medications are known to interact with olanzapine. Includes amlodipine, gabapentin, lisinopril. You should not take gabapentin with other drugs that can cause drowsiness, such as: benzodiazepines (e.g., Xanax, Valium), barbiturates (e.g., phenobarbital), narcotics (e.g., codeine, oxycodone), certain antidepressants (e.g., amitriptyline, trazodone), muscle relaxants (e.g., carisoprodol, cyclobenzaprine), or antihistamines (e.g Adding olanzapine to gabapentin. Gabapentin is eliminated unchanged by the kidney for 100%. Olanzapine is principally metabolized by CYP1A2 and CYP2D6. This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects. [5] Olanzapine is a second-generation (atypical) antipsychotic medication. The FDA has approved this medication for schizophrenia if the patient is over the age of 13 and bipolar disorder, including mixed or manic episodes. Olanzapine is also approved for use with fluoxetine, a selective serotonin reuptake inhibitor (SSRI), in patients with episodes of depression associated with bipolar disorder Review detailed drug interaction details between Gabapentin and Olanzapine, including severity, interaction details, how to manage the interaction, and more. Using gabapentin together with OLANZapine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. Use WebMD's drug interaction checker to find which medications, vitamins, or supplements may be unsafe to combine. Zyprexa (olanzapine) is an atypical antipsychotic that may be used to treat adults and adolescents aged 13 and older with schizophrenia or bipolar I disorder. For bipolar I disorder, it may be used alone for manic or mixed episodes, or in combination with There are many medications, supplements, and foods that can interact with olanzapine because of how it’s broken down in the body. Carbamazepine (Tegretol), alcohol, and blood pressure medications are a few examples of things that can cause an interaction. Olanzapine is used to treat schizophrenia, bipolar disorder, and depression. Learn about side effects, drug interactions, dosages, warnings, and more. Olanzapine oral tablet is a prescription drug used to treat schizophrenia, depression, and bipolar I disorder. It comes as a regular tablet and an orally disintegrating tablet. It’s available in
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