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Whether you are taking gabapentin for nerve pain, seizures, or other conditions, it is important to be aware of the drugs that should not be taken with this medication. Gabapentin is a common prescription drug that is used to treat a variety of conditions, and it is important to understand the potential interactions with other drugs and what to avoid. In this article, we’ll discuss the drugs Therefore, phenytoin and gabapentin can induce thyroid hormone imbalance in different ways and administering these AEDs concomitantly could increase the possibility of severe clinical hypothyroidism. Gabapentin and Dilantin are two medications commonly used to manage different medical conditions. Gabapentin, a medication for seizures, postherpetic neuralgia, and restless legs syndrome, and Dilantin, an anticonvulsant for epilepsy and seizures, are both prescribed to a wide population of patients. However, it is essential to consult a healthcare professional before taking these medications A Moderate Drug Interaction exists between gabapentin and Phenytoin Sodium. View detailed information regarding this drug interaction. Some of the main substances that interact with gabapentin are morphine, caffeine, losartan, ethacrynic acid, phenytoin, mefloquine and magnesium oxide. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy. A phase IV clinical study of FDA data: drug interactions are found among 358 people who take Gabapentin (gabapentin) and Dilantin (phenytoin sodium). The present case is a warning of the possible interaction of a drug (gabapentin) not contemplated when starting or when monitoring an antiepileptic treatment. 862 medications are known to interact with phenytoin. Includes amlodipine, gabapentin, atorvastatin. Drug interactions are reported among people who take Gabapentin (gabapentin) and Phenytoin (phenytoin). Common drug interactions include depressed mood among females and drug ineffective among males. The phase IV clinical study analyzes what interactions people have when they take Gabapentin and Phenytoin, and groups them by gender, age and more. A Moderate Drug Interaction exists between Dilantin and gabapentin. View detailed information regarding this drug interaction. 862 medications are known to interact with Dilantin. Includes amlodipine, gabapentin, atorvastatin. Request PDF | Possible gabapentin-phenytoin interaction | We report a possible case of gabapentin induced phenytoin toxicity. White man, 26 years old, chronically treated with phenytoin (for the Gabapentin has shown no effect on phenytoin (Dilantin), carbamazepine (Tegretol), valproic acid (Depakene) and phenobarbital levels (Table 2). No clinically important interaction has been Abstract Patients with cancer commonly experience seizures. Combined therapy with anticonvulsant drugs (AEDs) and chemotherapeutic drugs or tyrosine kinase inhibitors carries inherent risks on drug-drug interactions (DDIs). In this review, pharmacokinetic studies of AEDs with chemotherapeutic drugs, tyrosine kinase inhibitors, and glucocorticoids are discussed, including data on maximum Gabapentin is often prescribed alongside other anticonvulsants like phenytoin, valproic acid, and phenobarbital to manage various epilepsy disorders, and it generally does not exhibit significant interactions with these medications. Compare Gabapentin vs Phenytoin head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Therefore, phenytoin and gabapentin can induce thyroid hormone imbalance in different ways and administering these AEDs concomitantly could increase the possibility of severe clinical hypothyroidism. INTRODUCTION We report a possible case of gabapentin-induced phenytoin toxicity. CASE REPORT White man, 26 years old, chronically treated with phenytoin (for the past 4 years) and gabapentin (for the past 17 months). He was seen after complaining of dysarthria, ataxia and vertigo for the past 3 months, although having noted slight dizziness and a general, though undefined, indisposition from Abstract Some patients with difficult-to-treat epilepsy benefit from combination therapy with two or more antiepileptic drugs (AEDs). Additionally, virtually all epilepsy patients will receive, at some time in their lives, other medications for the management of associated conditions. In these situations, clinically important drug interactions may occur. Carbamazepine, phenytoin, phenobarbital Some of the main substances that interact with gabapentin are morphine, caffeine, losartan, ethacrynic acid, phenytoin, mefloquine and magnesium oxide. Some of the side effects caused by gabapentin are teratogenicity, hypoventilation, respiratory failure and myopathy.
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