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A Moderate Drug Interaction exists between gabapentin and tizanidine. View detailed information regarding this drug interaction. A Moderate Drug Interaction exists between gabapentin and Zanaflex. View detailed information regarding this drug interaction. A Moderate Drug Interaction exists between gabapentin and Zanaflex. View detailed information regarding this drug interaction. Tizanidine (Zanaflex) interacts with alpha-2 agonist drugs, birth control medications, opioids, sedatives, and other medications. Here’s what you should not take with tizanidine to avoid side effects. A phase IV clinical study of FDA data: drug interactions are found among 1,664 people who take Tizanidine hydrochloride (tizanidine hydrochloride) and Gabapentin (gabapentin). A phase IV clinical study of FDA data: drug interactions are found among 1,983 people who take Gabapentin (gabapentin) and Zanaflex (tizanidine hydrochloride). Compare Gabapentin vs Tizanidine head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Use Drugs.com’s Drug Interaction Checker, trusted by doctors and patients, to instantly review your meds for unsafe combinations. Use WebMD's drug interaction checker to find which medications, vitamins, or supplements may be unsafe to combine. GoodRx Health Tizanidine (Zanaflex) is a muscle relaxer that’s FDA approved to treat muscle spasticity. Spasticity occurs when your muscles are tight and stiff. If you’re prescribed tizanidine, knowing about possible tizanidine warnings, including drug interactions, can help keep you safe. Tizanidine interactions can change the way tizanidine works in your body or could raise the risk of Learn common interactions when taking gabapentin (Neurontin), such as other medications and alcohol. Review detailed drug interaction details between Gabapentin and Tizanidine, including severity, interaction details, how to manage the interaction, and more. A Moderate Drug Interaction exists between Neurontin and Zanaflex. View detailed information regarding this drug interaction. The drugs below are categorized by the severity of their interaction (see description of categories at the bottom of the page). Click the drug name (listed by the generic name) to view specific drug-drug interaction details. An AI-powered real world drug study: drug interactions are found among 2,673 people who take Neurontin (gabapentin) and Zanaflex (tizanidine hydrochloride). Drug interactions can significantly affect the effectiveness of gabapentin. When taken with certain other medications, the absorption or metabolism of gabapentin may be altered, leading to either reduced efficacy or increased side effects. Compare Gabapentin vs Zanaflex head-to-head with other drugs for uses, ratings, cost, side effects and interactions. Zanaflex Interactions There are 652 drugs known to interact with Zanaflex (tizanidine), along with 4 disease interactions, and 3 alcohol/food interactions. Of the total drug interactions, 249 are major, 401 are moderate, and 2 are minor. Muscle Relaxants Muscle relaxants like cyclobenzaprine (Flexeril), tizanidine (Zanaflex), baclofen, and methocarbamol (Robaxin) are sometimes used together with gabapentin, especially for conditions involving muscle spasms like fibromyalgia. However, combining these medications does increase side effects like drowsiness, dizziness, and fatigue. 652 medications are known to interact with tizanidine. Includes amlodipine, gabapentin, lisinopril.
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