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Adding gabapentin to olanzapine. Olanzapine is principally metabolized by CYP1A2 and CYP2D6. Gabapentin is eliminated unchanged by the kidney for 100%. This combination of drugs may have possible synergistic effects. There are no reports for pharmacokinetic drug interactions. However, the combination will have additional side effects. Olanzapine, sold under the brand name Zyprexa among others, is an atypical antipsychotic primarily used to treat schizophrenia and bipolar disorder. [12] It is also sometimes used off-label for treatment of chemotherapy-induced nausea and vomiting [13] and as an appetite stimulant. [14] For schizophrenia, it can be used for both new-onset disease and long-term maintenance. [12] It is taken by Review detailed drug interaction details between Gabapentin and Olanzapine, including severity, interaction details, how to manage the interaction, and more. Yes, there can be a "moderate" interaction between the 2 drugs. It's best to call your doctor and clarify their instructions. Thanks Good Luck. Description Olanzapine is used to treat schizophrenia. It may also be used alone or with other medicines (eg, lithium or valproate) to treat mania or mixed episodes that is part of bipolar disorder (manic-depressive illness). Olanzapine may also be used together with fluoxetine to treat depression that is a part of bipolar disorder, and depression in patients who received other antidepressants Zyprexa is an atypical antipsychotic used to treat schizophrenia, bipolar disorder, depression occurring with bipolar disorder & treatment resistant depression. Use WebMD's drug interaction checker to find which medications, vitamins, or supplements may be unsafe to combine. The phase IV clinical study analyzes what interactions people have when they take Zyprexa and Gaba. It is created by eHealthMe based on reports of 2 people who take the same drugs from the FDA, and is updated regularly. Olanzapine (Zyprexa) is an antipsychotic that can treat schizophrenia and bipolar disorder. It balances the levels of dopamine and serotonin in your brain. Drug interactions are reported among people who take Olanzapine (olanzapine) and Gabapentin (gabapentin). Common drug interactions include suicide attempt among females and drug ineffective among males. Gabapentin was added to ongoing antipsychotic treatment with olanzapine or risperidone for eight weeks. The primary outcome measure was the Positive and Negative Syndrome Scale (PANSS). Find patient medical information for Olanzapine (Zyprexa) on WebMD including its uses, side effects and safety, interactions, pictures, warnings, and user ratings ZYPREXA and some medicines may interact with each other and may not work as well, or cause possible serious side effects. Your doctor can tell you if it is safe to take ZYPREXA with your other medicines. Olanzapine (Zyprexa) is a medication that works in the brain to treat schizophrenia. Olanzapine is also known as a second-generation antipsychotic (SGA) or atypical antipsychotic, and rebalances dopamine and serotonin to improve thinking, mood, and behavior. There are many medications, supplements, and foods that can interact with olanzapine because of how it’s broken down in the body. Carbamazepine (Tegretol), alcohol, and blood pressure medications are a few examples of things that can cause an interaction. Zyprexa is a prescription medicine used to treat the symptoms of schizophrenia and bipolar disorder (manic depression). Learn about side effects, dosage, drug interactions, warnings, and more. 667 medications are known to interact with Zyprexa. Includes amlodipine, gabapentin, lisinopril. Zyprexa (olanzapine) is an atypical antipsychotic that may be used to treat adults and adolescents aged 13 and older with schizophrenia or bipolar I disorder. For bipolar I disorder, it may be used alone for manic or mixed episodes, or in combination with Applies to: gabapentin and Zyprexa (olanzapine) Using gabapentin together with OLANZapine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. Olanzapine may block the effects of agents used to treat Parkinson’s disease such as levodopa/carbidopa (Sinemet®), bromocriptine, pramipexole (Mirapex®), ropinirole (Requip®), and others.
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