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The association between gabapentin or pregabalin exposure and dementia risk was further examined with stratification according to sex, age, and comorbidities such as diabetes, hypertension, stroke, dyslipidemia, depression, and head injury. Gabapentin prescription in adults with chronic low back pain is associated with increased risk of dementia and cognitive impairment, particularly in non-elderly adults. Physicians should monitor cognitive outcomes in patients prescribed gabapentin. Regular gabapentin use appeared to increase risk of dementia by 29% and mild cognitive impairment (MCI) by 85%, researchers reported July 10 in the journal Regional Anesthesia & Pain Medicine. What’s more, the risk was more than doubled in people normally considered too young to suffer from brain aging, those 18 to 64, results show. Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI)—29% and To explore the association between gabapentin use and the risk of dementia in patients with chronic pain, considering the rising concerns of dementia Neurontin (generic name: gabapentin) was FDA-approved in 1993 for use as an anticonvulsant for people suffering from partial seizures associated with epilepsy. It is also FDA-approved for the The lawsuit has shed light on the possible link between Gabapentin and memory loss. As a result, this information can empower patients to make informed decisions about their treatment and discuss these concerns with their healthcare providers. Herein, we aimed to evaluate the association between gabapentin or pregabalin use and the risk of dementia. Methods: In this retrospective, population-based matched cohort study, all research data were collected from the 2005 Longitudinal Health Insurance Database, which contains data of 2 million people randomly selected from the National UNITED STATES DISTRICT COURT FOR THE DISTRICT OF NEW JERSEY SUMMARY NOTICE OF PROPOSED CLASS ACTION SETTLEMENT, MOTION FOR ATTORNEYS’ FEES, AND HEARING REGARDING SETTLEMENT TO: ALL PERSONS OR ENTITIES WHO HAVE PURCHASED NEURONTIN DIRECTLY FROM PFIZER, INC. AND WARNER-LAMBERT AT ANY TIME DURING THE PERIOD OF DECEMBER 11, 2002, THROUGH AUGUST 31, 2008 AND WHO HAVE ALSO PURCHASED GENERIC Learn about the side effects of gabapentin, from common to rare, for consumers and healthcare professionals. We would like to show you a description here but the site won’t allow us. We describe a case where gabapentin was used to treat a patient with mixed Alzheimer's/vascular dementia presenting with severe aggression requiring hospitalization. The case is followed by a systematic review of current literature of the use of these drugs in aggression in patients with dementia. Explore the potential for seeking compensation in gabapentin-related memory loss cases, including legal grounds, evidence, and filing deadlines. Explore gabapentin's effects on mental function, memory, and cognition. Learn about managing side effects and balancing therapeutic benefits with potential risks. Especially in older adults, gabapentin is prescribed to treat behavioral and psychological symptoms of dementia (BPSD) (Kim et al., 2008). Several studies have reported that gabapentin has a deleterious effect on cognition (Leach et al., 1997; Meador et al., 1999; Shem et al., 2018). Gabapentin lawsuits arise from claims of serious side effects and insufficient warnings about risks associated with the medication. Gabapentin, which is used to treat seizures, nerve pain and restless leg syndrome might be linked with increased risk of dementia, a new study says. Gabapentin new users with normal cognition at the visit of gabapentin initiation (i.e., index visit) were included. New-users were matched on year of first enrollment and time of gabapentin initiation since enrollment to randomly select nonusers with replacement. In rare cases like frontotemporal lobar degeneration (a dementia-related condition), gabapentin showed *neuroprotective* effects in lab studies [4], but human data remains limited here. **Who’s Most at Risk?** Older adults are particularly vulnerable due to age-related brain changes [1]. Frequent use of common pain drug linked to increase in dementia and cognitive decline, study suggests.
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